Hoboken, NJ to Spartanburg, SC buses and trains from $120

Here are some trips other travelers have found on Routefriend.
$120
14h 28m
1 stop
BoltBus Amtrak
$125
15h 43m
1 stop
GotoBus Amtrak
$200
15h 31m
2 stops
NJTransit Amtrak