Jamestown, NY to University of Pennsylvania buses and trains from $112

Or, see buses and trains from University of Pennsylvania to Jamestown, NY.
Here are some trips other travelers have found on Routefriend.
$112
22h 36m
4 stops
Amtrak NJTransit
$115
22h 36m
4 stops
Amtrak NJTransit
$150
16h 10m
2 stops
Amtrak