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Poughkeepsie, NY to Carnegie Mellon University buses and trains from $56
Here are some trips other travelers have found on Routefriend.
$56
9h 24m
1 stop
 Metro-North Greyhound
$58
10h 0m
1 stop
 Amtrak Greyhound
$96
11h 4m
1 stop
 Metro-North Amtrak
$114
14h 27m
2 stops
 Amtrak Amtrak
$114
14h 27m
2 stops
 Amtrak
$119
15h 18m
3 stops
 Metro-North Amtrak
$?
13h 49m
2 stops
 Metro-North Amtrak
$?
14h 25m
2 stops
 Metro-North Amtrak