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Charlottesville, VA to University of South Carolina-Columbia buses and trains from $70
Here are some trips other travelers have found on Routefriend.
$70
18h 3m
1 stop
 Amtrak Megabus
$72
11h 45m
1 stop
 Amtrak Megabus
$120
16h 52m
1 stop
 Amtrak